NBA pick of the day · Thu, Oct 22 · 7:00 PM ET
Cleveland Cavaliers at Philadelphia 76ers
Philly Opens the Home Floor With Cleveland as the Victim
The pick: Philadelphia 76ers -3.5 at −105 (FanDuel)
Won. Final: Cleveland Cavaliers 106, Philadelphia 76ers 114.
Philadelphia hosts its home opener tonight against a Cleveland team playing its first regular-season game of 2026-27, and the 76ers are a 3.5-point favorite at -105 on FanDuel. The single biggest reason to back Philly covering is the most basic one: Joel Embiid and Tyrese Maxey already have a 2026-27 game in their legs, and the Cavaliers are walking in with none.