Pick of the Day · Thu, Mar 19 · 1:30 PM ET

South Florida Bulls at Louisville Cardinals

South Florida Bulls +4.5

The pick: South Florida Bulls +4.5 at −110

Won. Final: South Florida Bulls 79, Louisville Cardinals 83.

The 25-8 South Florida Bulls have demonstrated superior consistency throughout the season and enter this NCAA tournament game with a better overall record than the 23-10 Louisville Cardinals. With no injuries reported on either side, this game should be tightly contested, making the 4.5-point spread too generous for Louisville. South Florida's strong regular season performance suggests they can keep this game within one possession or potentially win outright.

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